比阿培南致继发性血小板增多症病例报告并文献复习

A case report of reactive thrombocytosis induced by Biapenem and review of literature

目的:提高对碳青霉烯抗生素不良反应的认识。方法:报道1例外伤并感染患者使用比阿培南而导致继发性血小板增多症,并且复习碳青霉烯类抗生素不良反应相关文献。结果:停用比阿培南1周后,该患者血小板逐渐降至正常。结论:碳青霉烯类抗生素有可能引起血小板增多症,临床需关注由此可能导致的血管栓塞等不良反应。

Objective ： To improve the understanding of adverse reactions of Carbapenems. Methods ： A case of reactive thrombocytosis induced by Biapenem was reported and the adverse reactions of Carbapenems were reviewed with literatures. Results： The blood platelets counts reduced to normal a week later after discontinuing Carbapenems. Conclusions： Thrombo- cytosis can be caused by Carbapenems. We should pay attention to such adverse reactions in clinical practice.