摘要
[目的]观察中药外洗、拔罐联合西药治疗慢性胆汁淤积性肝病皮肤瘙痒疗效。[方法]使用随机平行对照方法,将86例门诊及住院患者按住院病志号法简单随机分为两组。两组均复方甘草酸苷,60m L/次,1次/d;还原型谷胱甘肽,1片/d,1次/d;熊去氧胆酸,1粒/次,3次/d。对照组43例炉甘石洗剂外敷(10°~15°)足底、双下肢、手掌、前臂,30min/次,1次/d。治疗组43例中药外洗(茵陈200g,苦参400g,黄柏200g,川楝子100g,赤芍300g,白鲜皮200g),以水浸泡30min,加热煮沸,再以小火煎煮20min,得到2000m L药液,以毛巾蘸取药液擦洗瘙痒部位(足底、双下肢、手掌、前臂),每次擦洗20~25min,3次/d;拔罐,取脾腧穴、胆俞穴、肝腧穴,留罐5min,以皮肤轻度充血为度,瘙痒部位闪罐治疗5min;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、皮肤损伤(程度、面积、瘙痒)、恢复时间、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈7例,显效13例,有效19例,无效4例,总有效率90.70%。对照组痊愈2例,显效21例,有效10例,无效10例,总有效率76.74%。治疗组疗效优于对照组(P〈0.05)。皮肤损伤(程度、面积、瘙痒)、恢复时间(皮损好转、止痒起效)治疗组优于对照组(P〈0.05)。[结论]中药外洗、拔罐联合西药治疗慢性胆汁淤积性肝病皮肤瘙痒效果显著,值得推广。
[ Objective ] To observe the wash outside medicine, cupping combined western medicine treatment of chronic cholestatie liver disease itchy skin effect. [ Methods ] Random parallel control method, 86 cases of outpatient and inpatient inpatient Chi by Law No. simple randomized into two groups. Both groups were glyeyrrhizin, 60mL / times, 1 times / d. Glutathione, a / d, 1 times / d. Ursodeoxycholic acid, 1 / time, 3 times / d. The control group 43 cases topical calamine lotion ( 10° - 15 ° ) foot, leg, hand, forearm, 30min / times, 1 times / d. Chinese medicine treatment group, 43 cases outside wash ( Yinchen 200g,Kushen400g, Huangbai 200g, Chuanjizi 100g, Chishao300g, Baixianpi 200g ) , water immersion 30min, heated to boiling, and then to a small fire boiling 20min, get 2000mL liquid, with a towel dipped in liquid scrub itching parts ( foot, leg, hand, forearm ) , each scrub 20-25min, 3 times / d. Cupping, acupoints spleen, gall shu, liver acupoints, leaving cans 5min, the degree of skin mild hyperemia; itching site flash tank treatment 5min. Western medicine with the control group. 14d is a continuous course of treatment. Observation of clinical symptoms, skin damage index, recovery indicators adverse reactions. A course of treatment to determine efficacy. [ Results ] The cure 7 cases, 13 cases were markedly effective in 19 cases, 4 cases, the total efficiency of 90.70%. The control group recovered two cases were cured, 21 cases, 10 cases, 10 cases, the total efficiency of 76.74%. Treatment group than the control group ( P〈0.05 ) . Both groups to improve skin damage index ( P〈0.05 ) , improvement in the treatment group than the control group ( P〈0.05 ) . Recovery indicators treatment group than the control group ( P〈0.05 ) . [ Conclusion ] Wash outside medicine, cupping combined western medicine treatment of chronic eholestatic liver disease itchy skin effect is significant, it is worth promoting.
出处
《实用中医内科杂志》
2014年第11期102-104,共3页
Journal of Practical Traditional Chinese Internal Medicine
关键词
慢性胆汁淤积性肝病皮肤瘙痒
中药外洗
拔罐
复方甘草酸苷
还原型谷胱甘肽
熊去氧胆酸
皮肤损伤
瘙痒
随机平行对照研究
Chronic cholestatic liver disease pruritus
Outside medicine wash
Cupping
Glycyrrhizin
Glutathione tablets
Ursodeoxycholic acid
Skin lesions ( Lesion extent, The lesion area, Pruritus )
Recovery index ( Skin lesions improved, Itching onset )
Randomized parallel group study