摘要
脑血管痉挛(cerebral vasospasm,CVS)是动脉瘤性蛛网膜下腔出血( Aneurysmal subarachnoid hemorrhage,aSAH)患者残疾甚至死亡的一种重要原因,其在aSAH患者中的发病率约为30%~70%[1-2]。此类患者发生延迟性神经功能缺失( delayed ischemic neurological deficit,DIND)的几率约为30%, CVS不仅可导致局部神经功能障碍,还可导致病患功能及认知恢复障碍。故如何防治CVS是降低aSAH病患致残率和病死率的关键。早期动脉瘤的处理,脑池内血凝块的清除,早期足量全程的尼莫地平的使用、镁剂、“3H”治疗、血管内介入治疗等措施,在一定程度上改善了患者的预后[3],尽管如此,因CVS发生比例较高,如何防治CVS仍是学者们不懈追求的目标。
出处
《临床神经外科杂志》
CAS
2014年第6期475-478,共4页
Journal of Clinical Neurosurgery
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