兰索拉唑联合中药治疗湿热中蕴型十二指肠溃疡的临床研究

Clinical Study on Lansoprazole Combined with Traditional Chinese Medicine in the Treatment of Damp-heat Stasis in the Middle-jiao Duodenal Ulcer

目的:探讨兰索拉唑联合中药治疗湿热中蕴型十二指肠溃疡的临床效果。方法:将临床诊断为湿热中蕴型十二指肠溃疡90例患者,随机分为兰索拉唑对照组、中药对照组和兰索拉唑联合中药治疗组(以下简称联合用药组),每组30例患者,对比观察分析疗效差异。结果:兰索拉唑对照组和中药对照组总有效率分别为66.67%和70.00%,联合用药组总有效率为96.67%,其临床疗效明显优于对照组,统计学有显著性差异;可有效促进溃疡愈合,明显改善证候,缓解临床症状。结论:兰索拉唑联合中药治疗湿热中蕴型十二指肠溃疡,能明显提高疗效,缓解证候,改善症状,应进一步扩大临床应用研究。

Objective：To investigate the clinical effect of lansoprazole combined with traditional Chinese medicine for treating damp- heat stasis in the middle-jiao of duodenal ulcer. Methods： 90 cases of clinical diagnosed belongs to damp-heat stasis in the middle-jiao of duodenal ulcerpatientsin our hospital, were randomly divided into control group （two groups） and treatment group （one group）. Each group was of 30 cases. Lansoprazole by western medicine group of lansoprazole treatment; the control group using traditional Chinese medicine for the treatment of traditional Chinese medicine; combined treatment group of lansoprazole combined with traditional Chinese medicine treatment, comparative observation of the clinical effects of three groups. Results：Lansoprazole control group and traditional Chinese medicine control group total effectiveness respectively is 66. 67% and 70. 00%, treatment group total efficiency is 96. 67% , the clinical therapeutic effect of the combined treatment group was significantly better than the control group（P 〈 0. 05）. Treatment group and control group, there was statistical significance between the data. Conclusion： The efficacy of lansoprazole combined with traditional Chi- nese medicine can be effective in the treatment of damp-heat stasis in the middle-jiao of duodenal ulcer, the clinical treatment of the total efficiency is improved obviously, be worth to popularize.