易栓症与不良妊娠结局的病理改变

妊娠期血液处于高凝状态是生理性的血栓前状态,遗传性和获得性易栓症增加了孕妇血栓形成的几率。虽然易栓症与胎盘介导的妊娠期并发症相关,但是否为直接原因仍未证实。妊娠期易栓症不具备特征性的胎盘病变,故易栓症及妊娠不良结局与胎盘异常病理之间的关系值得进一步研究。

Pregnancy is a physiological prothrombotic state. Genetic and acquired thrombophilia increases the risk of maternal thrombophilia. Thrombophilia is not yet established as a cause of the placenta-mediated pregnancy complications, although the association between thrombophilia and placentamediated pregnancy complications is demonstrated. Maternal thrombophilia do not have a characteristic placental lesions. Future study on the relationship of abnormal placental pathology of poor pregnancy outcomes and thrombophilia should be considered.