急性心肌梗死后心力衰竭患者体内BNP的变化

Changes in BNP in Patients with Heart Failure after Acute Myocardial Infarction

目的研究分析急性心肌梗死后心力衰竭患者的B型钠尿肽变化。方法根据我院接收的77例急性心肌梗死后心力衰竭换来进行研究分析，观察患者的住院期间和出院半年后的心血管不良事件发生率，心力衰竭患者受到血浆B性钠尿肽变化的影响。结果健康组患者他们的血浆B型钠尿肽比心功能Ⅲ和Ⅳ级患者相比要低一些，经过治疗后，Ⅱ、Ⅲ、Ⅳ级患者均较治疗前的B型钠尿肽水平有所下降。临床中患者的B型钠尿肽水平超过250pmol／L的病例要比低于该水平的病例其心血管不良事件发生率几率更高一些。临床中患者的B型钠尿肽水平越高，其心衰特异性越强，敏感性越低，80-120pmol／mL是其最佳阀值。结论B型钠尿肽是患急性心结梗死后心力衰竭患者的重要诊断指标和治疗参考依据。

Objective To study the analysis of B type natriuretic peptide changes in patients with heart failure after acute myocardial infarction. Methods According to our hospital received 77 cases of acute congestive heart failure after myocardial infarction in exchange for research and analysis, the incidence rate of the patients were observed during hospitalization and discharge after six months of adverse cardiovascular events, the effect of plasma of natrinretic peptide by B changes in patients with heart failure. Results Peptide their plasma type B natriuretic health group than in patients with cardiac function in patients with stage Ⅲ and Ⅳ compared to lower, after treatment, Ⅱ、Ⅲ、Ⅳ patients were compared with those before treatment or B type natriuretic peptide levels drop. Clinical in patients with B type natriuretic peptide levels in more than 250 cases of pmol/L than below the level of the cases of cardiovascular adverse event rates higher chance of some. Clinical in patients with B type natriurefic peptide level is higher, the heart failure specific more strong, sensitivity is low, 80 - 120 pmol/mL is the best threshold. Conclusion B type natrinretic peptide is important index of diagnosis and treatment of reference in patients with heart failure after acute heart infarction.