胺碘酮治疗慢性心力衰竭并发室性心律失常56例临床分析

Chronic Heart Failure Complicated by Ventricular Arrhythmias Amiodarone Therapy Clinical Analysis of 56 Cases

目的：探究胺碘酮治疗慢性心力衰竭并发室性心律失常的疗效，分析其优势。方法将2014年1月～2014年5月到我院诊治的56例慢性心力衰竭并发室性心律失常的患者随机分为对照组（实施常规抗心力衰竭治疗）和实验组（常规抗心力衰竭治疗＋胺碘酮治疗）每组28例，观察两组的左心室射血分数（LVEF%）和二尖瓣口舒张早期和舒张晚期血流峰值计算E峰/A峰（E/A），心律失常，心功能改善情况，比较其差异。结果观察组内的治疗前后LVE、E/A资料分析后P〈0.05，差异显著，对照组内治疗前后的LVEF、E/A的资料分析结果为P〉0.05；在心功能改善方面差异显著（P〈0.05）。结论胺碘酮可以为慢性心力衰竭并发室性心律失常的患者减少痛苦和并发症的发生，但仍应继续研究其长期的有效性和安全性。

Objective To explore the efficacy of amiodarone in the treatment of chronic heart failure complicated by ventricular arrhythmias,analyze its advantages.Methods Patients wil be in January 2014~May 2014 to our hospital for treatment of 56 cases of chronic heart failure complicated by ventricular arrhythmias were randomly divided into control group （implementation of the conventional anti-heart failure treatment） and the experimental group （conventional anti-heart failure therapy plus amiodarone） in each group, 28 cases were observed in left ventricular ejection fraction （LVEF%） and diastolic mitral peak early and late diastolic blood flow is calculated peak E/A peak（E/A）,rhythmias, heart function improve the situation, compare their differences. ResultsBefore and after treatment LVE observed within the group, E / A data after analysis of P 〈0.05, significant difference, in the control group, LVEF before and after treatment, data analysis results E / A for P〉 0.05; heart function improvement were significantly different （P 〈0.05）.ConclusionAmiodarone can reduce pain and complications for patients with chronic heart failure complicated by ventricular arrhythmias, but should continue to study the long-term effectiveness.