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大剂量辛伐他汀强化治疗对缺血性脑血管病患者脑血管储备能力的影响 被引量:6

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摘要 目的研究大剂量辛伐他汀强化治疗对缺血性脑血管病患者脑血管储备能力的影响。方法选取2012年6月~2014年5月期间收治的100例缺血性脑血管病患者纳入研究,根据降脂治疗方法不同分为两组,观察组患者给予大剂量辛伐他汀治疗,对照组患者给予常规剂量辛伐他汀治疗,采用酶联免疫吸附法检测血清炎症因子、彩色多普勒超声检测大脑中动脉的血管储备能力。结果观察组患者的炎症因子C反应蛋白、肿瘤坏死因子-α、基质金属蛋白酶-9含量以及血管储备能力、屏气指数均低于对照组,差异均具统计学意义(P〈0.05)。结论大剂量辛伐他汀强化治疗有助于缓解炎症反应、提高脑血管储备能力,是缺血性脑血管病理想的治疗方法。
作者 姜建萍
出处 《中国处方药》 2015年第1期71-72,共2页 Journal of China Prescription Drug
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