期刊文献+

单纯性肥胖与血管紧张素Ⅱ的关系研究

下载PDF
导出
摘要 目的探讨单纯性肥胖与血管紧张素Ⅱ水平的关系。方法选取单纯性肥胖患者100例。分别设为轻度肥胖组39例,中度肥胖组42例,重度肥胖组19例。同时选取同期体检健康的人100例,设为对照组。检查受试者BMI指数及血管紧张素Ⅱ水平。结果轻、中、重度肥胖组患者BMI指数及血管紧张素Ⅱ水平均显著高于对照组(P〈0.01)。且3组间比较发现随着肥胖程度加重其BMI指数及血管紧张素Ⅱ水平随之升高,组间差异有统计学意义(P〈0.01)。结论单纯性肥胖患者血管紧张素Ⅱ高于健康人群,血管紧张素Ⅱ与肥胖及肥胖相关性疾病有相关性。
出处 《实用临床医药杂志》 CAS 2014年第E02期129-129,131,共2页 Journal of Clinical Medicine in Practice
  • 相关文献

参考文献5

二级参考文献60

  • 1武阳丰,马冠生,胡永华,李艳平,李贤,崔朝辉,陈春明,孔灵芝.中国居民的超重和肥胖流行现状[J].中华预防医学杂志,2005,39(5):316-320. 被引量:567
  • 2Yusuf S, Gerstein H, Hoogewerf B, et al. Ramipril and the development of diabetes[ J]. JAMA,2001,286 ( 15 ) : 1882-1885.
  • 3The ALLHAT officers and coordinators for the ALLHAT collaborative research group. Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care:the antihypertensive and lipid-lowering treatment to prevent heart attack trial ( ALLHAT-LLT ) [ J ]. JAMA, 2002, 288: 2998-3007.
  • 4The Dream Trial Investigators. Effect of ramipril on the incidence of diabetes [ J ]. N Engl J Med ,2006,355 ( 15 ) : 1551-1562.
  • 5Julius S, Kjeldsen SE, Weber M, et al. Outcomes in hypertensive patient at high cardiovascular risk with regimens based on valsartan or amlodipine:the VALUE randomized trial[ J]. Lancet,2004,363 ( 9426 ) : 2002 -2031.
  • 6Lindholm LH,Ibsen H, Borch-Johnsen K,et al. Risk of new-onset diabetes in the Losartan intervention For Endpoint reduction in hypertension study [ J ]. J Hyperten, 2002,20 (9) : 1879-1886.
  • 7Pfeffer MA, Swedberg K, Granger CB, et al. Effects of candesartan on mortality and morbidity in patient with chronic heart failure:the CHARM-Overall programme [ J ]. Lancet, 2003, 362 ( 9386 ) : 759-766.
  • 8Taniguchi CM,Emanuelli B, Kahn CR. Critical nodes in signaling pathways :insights into insulin action [ J ]. Nat RevMol Cell Biol, 2006,7(2) :85-96.
  • 9LeRoith D. Beta-cell dysfunction and insulin resistance in type 2 diabetes: role of metabolic and genetic abnormalities [ J ]. Am J Med ,2002,113 ( Suppl 6A) :3S-11S.
  • 10Verma S, Bhanot S, MeNeill JH. Sympathectomy prevents fructose induced hyperinsulinemia and hypertention [ J ]. Eur J Pharmacol, 1999,373 ( 3 ) : R1 -R4.

共引文献53

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部