丹参水溶性化合物抗心肌缺血作用的研究进展

Research advances in protective effects of water soluble compounds in Salvia miltiorrhiza against myocardial ischemia

丹参为唇形科植物丹参的干燥根及根茎,其水溶性化合物被公认为是丹参抗心血管疾病的活性成分。该文查阅近年来国内外研究文献,从预防、治疗及防治再灌注损伤等多层次药理作用对丹参水溶性化合物抗心肌缺血作用进行综述,为丹参中活性单体成分及其复方制剂的研发提供理论依据。

Salvia miltiorrhiza is dry root or rhizome of the labiatae plant Salvia miltiorrhiza,whose water-soluble ingredients are recognized as its bioactive components in cardiovascular diseases. Based on researches at home and abroad in recent years,this article summarizes pharmacological effect resisting myocardial ischemia of Salvia miltiorrhiza's water soluble compounds in multi-level from the prevention,treatment and anti-reperfusion damage,to provide theoretical basis for the research and development of the active monomers in Salvia miltiorrhiza and compound preparations.