儿童上皮源性涎腺肿瘤患儿122例的临床分析

Clinical analysis of 122 cases of pediatric epithelial salivary tumors

目的:分析儿童上皮源性涎腺肿瘤患儿的临床特点。方法:回顾性分析1987年-2011年小于19岁的涎腺肿瘤患儿的临床资料。结果:122例患儿,105例为良性,17例是恶性。最易受累的部位是患儿的腮腺。在良性病例中,混合瘤占91.4%,恶性病例中,黏液表皮样癌占47.1%。1例患儿诊断为腺淋巴瘤。在我们的随访中,所有患儿均未出现颈部复发。恶性涎腺肿瘤患儿的5年和10年生存率分别是81.8%和66.7%。结论:上皮源性涎腺肿瘤少见,混合瘤和黏液表皮样癌是最常见的病理类型,恶性涎腺瘤患儿的预后较差。

Objective：To analyze clinical characteristics of pediatric epithelial salivary tumors. Methods：The clinical data of the patients less than 19 years old with salivary tumor from 1987 to 2011 were retrospectively analyzed. Results：122 children patients were included in our study, 105 tumors were benign and 17 were malignant. The most common involved site was parotid gland, pleo-morphic adenoma represented 91. 4% in benign group, and mucoepidermoid carcinoma represented 47. 1% in malignant group. War-thin＆#39;s tumor was diagnosed in one patient. In our follow-up, no regional recurrences occurred in the patients without neck dissection. The 5- and 10-year overall survival rates of the patients with malignant salivary tumors were 81. 8% and 66. 7%, respectively. Con-clusions：Epithelial salivary tumor is rare, pleomorphic adenoma and mucoepidermoid carcinoma are the most common benign and ma-lignant tumor, respectively. The prognosis of the patients with malignant salivary tumors is not very favorable.