渗出性老年黄斑变性的光学相干断层扫描

Optical coherence tomography of exudative age-related macular degeneration and choroidal neovascularization

目的 观察渗出性老年黄斑变性黄斑部新生血管膜的形态改变。方法 对42例49眼渗出性老年黄斑变性的黄斑部进行光学相干断层扫描和荧光造影检查,并对二者的结果进行比较。结果 渗出性老年黄斑变性黄斑部光学相干断层扫描图像显示黄斑部新生血管膜有4种表现,即边界清晰的新生血管膜21眼（42.8％）。边界不清的新生血管膜15眼（30.6％）。纤维血管性色素上皮脱离6眼（12.3％）和出血性色素上皮脱离7眼（14.4％）;与荧光造影比较显示边界清晰的新生血管膜和纤维色素上皮脱离多表现为典型的新生血管膜,边界不清的新牛血管膜和出血性色素上皮脱离多表现为隐匿性新生血管膜。结论 光学相干断层扫描能够确定脉络膜新生血管膜的形态,并对脉络膜新生血管膜的层次和边界进行定位。

Objective To investigate the cross-sectional imaging of retina in patients with exudative aged-related macular degeneration (AMD) and choroidal neovascularization (CNV). Methods Optical coherence tomography ( OCT ) and fluorescein angiograms (FA) were performed on 42 patients (49 eyes) with clinical diagnosis of AMI). Results Exudative AMD and CNV distributed among the four following categories : well-defined CNV in 21 eyes (42. 8% ) , poorly defined CNV in 15 eyes ( 30. 6% ) , fihrovascular pigment epithlium detachment ( PED ) in 6 eyes ( 12. 2% ) and hemorrhagic PED in 7 eyes ( 14. 4% ). Classic CNV on fluorescein angiograms presented both as well-defined and as fibrovascular PED. Angiograpliically occulted CNV which appeared well defined on OCT was sometimes dues the presence ol hemorrhage blocking the FA. Poorly defined CNV and hemorrhagic PED on OCT showed occult CNV. Conclusions OCT is able lo delect and locale CNV in morphology. OCT is useful in assessing possible subfoveal involvement of CNV.