中西医结合疗法治疗肝癌78例疗效观察

Clinical Observation of Integrated Chinese and Western Medicine Therapy for Treatment of Liver Cancer:A Report of 78 Cases

目的:观察中西医结合疗法对肝癌患者的临床治疗效果。方法:回顾性分析156例肝癌患者,按治疗方法分为治疗组和对照组各78例,治疗组给予中西医结合治疗,对照组只给予西医治疗,疗程均为3月。对比2组的治疗效果及生化指标如碱性磷酸酶(ALP)、γ-谷氨酰转肽酶(γ-GP)、谷丙转氨酶(ALT)及总胆红素(TBil)的水平。结果:对照组总有效率为48.7%,观察组总有效率为71.8%,2组比较,差异有非常显著性意义(P<0.01)。2组治疗前ALP、γ-GP、ALT及TBil分别比较,差异均无显著性意义(P>0.05)。治疗后,2组ALP、ALT及TBil值均较治疗前升高(P<0.05),观察组的ALP、ALT及TBil值均低于对照组(P<0.05)。观察组生活质量提高率高于对照组,下降率低于对照组,差异均有非常显著性意义(P<0.01)。结论:中西医结合疗法治疗肝癌患者,可提高治疗效果,改善患者的生活质量。

Objective： To observe the clinical effect of integrated Chinese and western medicine therapy for the treatment of liver cancer. Methods. Clinical data of 156 cases of liver cancer were retrospectively analyzed. The chosen cases were divided into two groups, 78 cases in each group. The observation group was given integrated Chinese and western medicine therapy and the control group received western medicine treatment alone. The treatment course lasted for three months. The changes of tumor size and clinical effect, and serum levels of alkaline phosphatase（ALP） and gamma -glutamyltranspeptidase（γ -GT）, and hepatic alanine aminotransferase（ALT） and total bilirubin（TSil） levels of the two groups were observed and compared. Results： The total effective rate was 71.8% in the observation group, and was 48.7% in the control group, the difference being significant（P 〈 0.01）. The differences of ALP, γ -G P, ALT and TBil between two groups before treatment was insignificant（P 〉 0.05）. The levels of ALP, ALT and TBil in both groups after treatment were increased （P 〈 0.05 compared with those before treatment）, and those in the observation group were lower than those in the control group（P 〈 0.05）. The improvement rate of quality of life in the observation group was higher than that in the control group（P 〈 0.05）. Conclusion： Integrated Chinese and western medicine therapy can improve the clinical effect and quality of life of liver cancer patients.