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食道癌合并胃癌患者实施奥沙利铂结合氟尿嘧啶治疗的效果 被引量:1

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摘要 目的:探讨食道癌合并胃癌患者实施奥沙利柏结合氟尿嘧啶治疗的临床疗效。方法按就诊顺序号将我院2010-01~2013-01间收治的32例食道癌合并胃癌患者分为对照组和观察组,每组患者16例。对照组给予顺铂结合氟尿嘧啶治疗,观察组给予奥沙利柏结合氟尿嘧啶治疗,比较两组患者的疗效及并发症发生情况。结果对照组无完全缓解病例,7例部分缓解,6例稳定,3例进展,总有效率为43.75%;观察组完全缓解2例,部分缓解11例,稳定2例,进展1例,总有效率为81.25%,组间比较差异具有统计学意义( P<0.05)。对照组发生恶心7例,呕吐4例,感觉神经障碍2例,消化道反应10例,白细胞及血小板下降5例,观察组发生恶心1例,呕吐2例,感觉神经障碍1例,消化道反应6例,白细胞及血小板下降1例,观察组各并发症或不良反应发生率均低于对照组。其中,恶心发生率明显低于对照组,比较差异具有统计学意义( P<0.05)。结论采用奥沙利柏结合氟尿嘧啶治疗食道癌合并胃癌的疗效较好,安全性较高,具有临床推广价值。
出处 《黑龙江医学》 2015年第1期46-47,共2页 Heilongjiang Medical Journal
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