1Collison LW, Workman C J, Kuo Tr,et al. The inhibitory eytokine IL- 35 contributes to regulatory T cell function [ J ]. Nature, 2007,450 ( 169 ) :566-569.
2Chaturvedi V, Collison LW, Guy CS, et al. Cutting edge: Human regu- latory T cells require IL-35 to mediate suppression and infectious toler- ance [ J ]. J Immuno1,2011,186 ( 12 ) :6661-6666.
3Jones LL, Vignali DA. Molecular interactions within the IL-6/IL-12 cytokine/receptor superfamily [ J ]. Immounol Res, 2011,51 ( 1 ) : 5- 14.
4Collison LW, Delgoffe GM, Guy CS, et al. The composition and signa- ling of the IL-35 receptor are unconventional [ J ]. Nat Immunol,2012, 13 ( 3 ) :290-299.
5Collison LW, Chaturvedi V, Henderson AL, et al. IL-35-mediated in- duction of a potent regulatory T cell population [ J ]. Nat Immunol, 2010,11 ( 12 ) : 1093-1101.
7Niedbala W, Wei XQ, Cai B, et al. IL-35 is a novel cytokine with ther- apeutic effects against collagen- induced arthritis through the expan- sion of regulatory T cells and suppression of Thl7cells [ J ]. Eur Immu- nol,2007,37( 11 ) :3021-3029.
8Kochetko'ca I, Golden S, I-Ioldemess K, et al. IL-35 stimulation of CD39 + regulatory T cells confers protection against collagen Ⅱ-in- duced arthritis via the production of IL-10 [ J ]. Immunol, 2010,184 (12) :1144-1153.
9Kuo J, Nardelli DT, Warner TF, et al. Interleukin-35 enhances Lyme arthritis in Borrelia-vaecinated and-infected mice [ J ]. Clin Vaccine Immunol,2011,18(7) :1125-1132.
10Whitehead GS,Wilson RH,Nakano K, et al. IL-35 production by in- ducible costimulator(ICOS)-positive regulatory T cells reverses es- tablished IL-17 dependent allergic airways disease[ J]. J Allergy Clin Immunol,2012,129 ( 1 ) :207-215.
4RICHARDSON P, MCKENNA W, BRISTOW M, et al. Report of the 1995 world health organization/international society and federation of cardiology taskforce on the definition and classification of cardiomyopathies [J]. Circulation, 1996, 93:841-- 842.
5NIEDBALA W, WEI X Q, CAI B, et al. IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells [J]. Eur J Immunol, 2007, 37:3021--3029.
6YANG J, YANG M, HTUT TM, et al. Epstein- Barr virus-induced gene 3 negatively regulates IL-17, Iil-22 and RORγt [J]. Eur J Immunol, 2008, 38: 1204--1214.
7COLLISON L W, WORKMAN C J, KUO T T, et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function [J]. Nature, 2007, 450:566--569.
8NIEUWENHUIS E E, NEURATH M F, CORAZZA N, et al. Disruption of T helper 2-immune responses in Epstien Barr virus-induced gene 3-deficient mice [J].Proc Natl Acad Sci U S A, 2002, 99..16951-- 16956.
9REDDY J, LLLES Z, ZHANG X, et al. Myelin proteolipid protein-special CD4^+ CD25^+ regulatory ceils mediate genetic resistance to experimental autoimmune encephalomyelitis [J].Proe Natl Aead Sci U S A, 2004, 101:15434--15439.
10COLLISON L W, VIGNALI D A. Interleukin-35: odd one out or part of the family? [J]. Immunol Rev, 2008, 226:248--262.
