壮医穴位刺血疗法治疗实热型失眠症30例

30 Cases of Heat- type Insomnia Patients Treated by Acupuncture Point Pricking Blood Therapy

目的观察壮医穴位刺血疗法治疗实热型失眠症的临床疗效并探讨其作用机理。方法将60例实热型失眠症患者分为2组各30例,壮医穴位刺血疗法治疗组,针刺对照组,对比观察治疗前后匹兹堡睡眠质量指数量表(PSQI)积分和实验室检测血浆中与睡眠密切相关的中枢神经递质5-羟色胺(5-HT)、去甲肾上腺素(NE)的含量变化指标。结果壮医穴位刺血疗法对实热型失眠症患者治疗前后匹兹堡睡眠质量指数量表(PSQI)入睡时间、睡眠质量的改善优于针刺对照组(P<0.05),而对睡眠时间、睡眠效率、睡眠困难、催眠药物和白天睡意的改善组间比较,差异均无显著性意义(P>0.05)。2组患者治疗前后PSQI总分值比较经统计学分析,差异具有非常显著性意义(P<0.01),说明2组对治疗失眠都有效,而治疗后组间总分比较,差异有显著性意义(P>0.05),说明壮医穴位刺血疗法治疗组对睡眠的改善优于针刺对照组。壮医穴位刺血疗法在明显提高血浆5-羟色胺(5-HT)含量的同时,也明显降低去甲肾上腺素(NE)的含量。结论壮医穴位刺血疗法治疗实热型失眠症疗效优于针刺对照组,其作用机制与调节血浆5-羟色胺(5-HT)和去甲肾上腺素(NE)代谢有关。

Objective： To observe the clinical effect of acupuncture point pricking blood therapy on the treatment of heat -type insomnia patients and explore its mechanism. Methods： 60 patients were divided into two groups, 30 per group, i. e. an acupuncture point pricking blood therapy group and an acupuncture group. Their Pittsburgh Sleep Quality Index（PSQI） integration and their central neurotransmitter serotonin（5 -HT） and norepinephrine（NE） indicator changes of laboratory plasma relating to sleep were observed and compared before and after the treatment. Results： The acupuncture point pricking blood therapy improved the sleep time and sleep quality of the patients in PSQI better than that of the acupuncture control group （ P 〈 0.05）, but the comparison of the sleep time, sleep efficiency, sleep difficulties, hypnosis drugs and daytime sleep improvement of the two groups showed no significant difference （ P 〉 0. 05 ）. The comparative and statistical analysis of PSQI total scores of the two groups before and after the treatment showed statistically significant difference （P 〈 0.01 ）, indicating the two acupuncture methods were effective to insomnia patients, but the comparison of the total scores of the two groups after the treatment showed the difference was statistically significant （ P 〉 0. 05 ）, indicating the acupuncture point pricking blood therapy had better effect than the acupuncture therapy. The acupuncture point pricking blood therapy significantly increased plasma 5 - HT and reduced NE at the same time. Conclusion： The acupuncture point pricking blood therapy has better effect on the treatment of heat - type insomnia patients and their mechanism is related to the regulation of plasma 5 - HT and the metabolism of NE.