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Nanog及其假基因Nanog P8在肿瘤中的研究进展

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摘要 随着肿瘤干细胞cancerstemcell,csc)学说的提出,干细胞相关基因在肿瘤发生中的作用日益被重视。Nanog是一种维持干细胞全能性的核转录因子,与包含POU结构域的Oct4(octamer—bindingtranscriptionfactor4)和包含HMG盒的Sox2(SexdeterminingregionY—box2,SRY—box2)共同维持胚胎干细胞的自我更新和多潜能性,被认为是胚胎干细胞的标志物之一。
出处 《天津医科大学学报》 2015年第1期90-92,F0003,共4页 Journal of Tianjin Medical University
基金 国家自然科学基金资助项目(81372844 81071731)
关键词 NANOG NANOG P8 肿瘤
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参考文献40

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