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甘精胰岛素联合那格列奈治疗初发2型糖尿病75例 被引量:2

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摘要 目的观察甘精胰岛素联合那格列奈治疗初发2型糖尿病的效果。方法 75例初发2型糖尿病患者予甘精胰岛素联合那格列奈治疗12周,观察治疗前后空腹血糖(FPG)、餐后2小时血糖(2h PG)、糖化血红蛋白(Hb A1c)及胰岛功能的变化。结果治疗后餐后2小时胰岛素、C肽水平略有升高,但差异无统计学意义;胰岛素分泌指数升高,胰岛素抵抗指数降低,治疗前后差异有统计学意义。结论甘精胰岛素联合那格列奈治疗初发2型糖尿病能控制血糖,恢复部分胰岛功能。
出处 《中国乡村医药》 2015年第1期22-23,共2页
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  • 1潘长玉,田慧,刘国良,李秀钧,傅祖植,陈家伟,暨亚洲糖尿病管理中国协作组.中国城市中心医院糖尿病健康管理调查[J].中华内分泌代谢杂志,2004,20(5):420-424. 被引量:193
  • 2王琼.甘精胰岛素联合口服格列美脲(亚莫利)治疗2型糖尿病的疗效观察[J].临床和实验医学杂志,2007,6(5):64-65. 被引量:3
  • 3Hanefeld M, Bounter K P, Dikision S, et al. Rapid and short - acting mealtime insulin secretion with nateglinide controls both prandial and mean glycemia. Diabetes Care, 2000, 23(2) :202.
  • 4Hu S, Wang S, Fanelli B, et al. Pancreatic beta-cell K(ATP) channel activity and membrane - binding studies with nateglinide: a comparison with sulfonylureas and repaglinide. J Pharmacol Exp Ther, 2000, 293 (2) :444.
  • 5Uehino H, Niwa M, Shimizu T, et al. Impairment of early insulin response after glucose load, rather than insulin resistance, is responsible for postprandial hyperglycemia seen in obese type 2 diabetes: assessment using nateglinide, a new insulin secretagogueo Endocr J, 2000, 47 (5) : 639.
  • 6World Health Organization.Definition,Diagnosis and Classification of Diabetes Mellitus and its Complications:Report of a WHO Consultation.Partl:Diagnosis and Classification of Diabetes Mellitus.Geneva,World Health Org,1999:1.
  • 7World Health Organization.Country and regional data.Availableat; http://www.who.int/diabetes/facta/world.figures/cn/.
  • 8Louis M,Helene L,Claude C.Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients:Variations with increasing levels of HbA1c.Diabetes Care,2003,26:881.
  • 9Kikichi M.Modulation of insulin secretion in non-insulin-dependent diabetes mellitusby two novel oral hypoglycaemic agents,NN623 and A4166.Diabet Med,1996,13:S151.
  • 10Yki-Jarvinen H,Dressier A,Ziemen M,H0E901/3002 Study Group:Less nocturnal hypoglycemia and better post-dinner glucose control with bedtime insulin glargine compare with bedtime NPH insulin during combination therapy in type 2 diabetes.Diabetes Care,2000,23:1130.

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