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Wnt信号通路调控骨髓间充质干细胞分化在肺部疾病治疗中的研究进展 被引量：1

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摘要 骨髓间充质干细胞是来源于骨髓的成体干细胞,与造血干细胞不同,它具有自我更新和多向分化潜能,被广泛应用于肺损伤的治疗中。Wnt信号通路可以调控骨髓间充质干细胞(MSCs)的增殖再生、分化、迁移等生物功能,与组织损伤后的重塑、损伤终止和组织修复或破坏密切相关。通过研究Wnt信号通路调控MSCs向不同表型及功能的成体细胞的分化过程及机理,为治疗肺损伤提供新思路和新方向。
作者 李燕 陆伟
机构地区 江苏省疾病预防控制中心
出处 《江苏预防医学》 CAS 2015年第1期48-50,共3页 Jiangsu Journal of Preventive Medicine
基金 国家自然科学基金(81301448)
关键词 骨髓间充质干细胞 再生医学 WNT信号通路 肺损伤 组织修复 调控
分类号 R563 [医药卫生—呼吸系统]
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参考文献17

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同被引文献25

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江苏预防医学
2015年 第1期

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