我院2013年707例住院患者抗精神病药应用现状分析

Analysis on application of antipsychotic drugs in 707 inpatients of our hospital in 2013

目的了解我院抗精神病药的使用现状,为临床合理用药提供依据。方法对我院2013年7月22日住院和新入院的精神病患者的用药情况进行分析。结果在707例患者中,使用1种抗精神病药治疗的患者有421例(59.97%),奥氮平位居首位(91例,12.87%),其余依次为喹硫平(64例,9.05%)、利培酮(58例,8.20%)、氯氮平(45例,6.37%);联合2种药物治疗的有207例(29.28%),以氯氮平+阿立哌唑、氯氮平+利培酮、奥氮平+利培酮多见。结论非典型抗精神病药占临床用药主导地位,两种抗精神病药物联合用药比例较2008年有所增加。

Objective To investigate the utilization of antipsychotic drugs in hospitalized patients of our hospital and provide reference for rational drug use. Methods The utilization of antipsychotic drugs in psychiatric inpatients in our hospital in July 22,2013 was surveyed and analyzed. Results 707 patients were treated with antipsychotic drugs. 421 patients were only treated with one kind of drug（ 59. 97%）,among which,the top 4 drugs in the list of utilization rate were olanzapine（ n = 91,12. 87%）,quetiapine（ n = 64,9. 05%）,risperidone（ n = 58,8. 20%）,clozapine（ n = 45,6. 37%）. 207 patients were treated with two kinds of drugs. The top combination treatment prescription were clozapine ＋ aripiprazole,clozapine ＋ risperidone,olanzapine ＋ risperidone. Conclusion The newtypical antipsychotic drugs take up the dominant position in the clinical treatment,and the proportion of combination drug use increased compared with 2008.