广州地区102例正常人紫外线最小红斑量测定

Detection of Minimal Erythema Does of Normal Skin to Ultraviolet Rays among 102 Healthy Volunteers in Guangzhou

目的:测定广州地区正常人紫外线最小红斑量(MED)的正常值范围,探讨其与性别、年龄、皮肤日光类型的关系。方法:以SUV1000型日光紫外模拟器作为照射光源,测定102名健康志愿者腹部正常皮肤的MED值(Ⅲ型、Ⅳ型皮肤)。结果:102名受试者MED均值:UVA为50.0 J/cm2,UVB为43.0 m J/cm2。不同皮肤类型间,Ⅲ型皮肤MED均值:UVA为38.5 J/cm2,UVB为36.1 m J/cm2;Ⅳ型皮肤MED均值:UVA为50.0 J/cm2,UVB为47.0 m J/cm2,Ⅳ皮肤MED均值均明显大于Ⅲ型皮肤(P值均<0.01)。不同性别间,男性MED均值:UVA为50.0 J/cm2,UVB为43.0 m J/cm2;女性:UVA为50.0 J/cm2,UVB为43.0 m J/cm2,不同性别间差异均无统计学意义(P值均>0.05)。不同性别的不同年龄阶段间UVA、UVB MED均值差异均无统计学意义(P值均>0.05);UVA-MED的正常值范围为≥30 J/cm2,UVBMED的正常值范围为≥29.1 m J/cm2。结论:紫外线MED的影响因素与皮肤日光反应类型有关,Ⅲ型皮肤UVA-MED、UVB-MED均明显低于Ⅳ型皮肤(P<0.01)。本组受试者MED与性别和年龄无直接关系。

Objective ：To investigate the minimal erythema does （MED） of normal skin to UV in Guangzhou city, and observe its relationship to gender, age and skin types. Methods： 102 healthy subjects were exposed to SUV1000, and the MED was measured. Results： The average MED value of all subjects to UVA was 50. 0 J/cm2, and to UVB was 43.0 mJ/cm2. In different skin types, MED value of skin type Ⅲ subjects to UVA was 38.5 J/cm2, and to UVB was 36. 1 mJ/cm2. MED value of skin type IV subjects to UVA was 50. 0 J/cm2, and to UVB was 47.0 mJ/ cm2. The value of type Ⅲ was lower significantly than the value of type IV （ P 〈 0. 01 ）. There was no statistical difference of MED value between men and female. And there was no significantly sta- tistical difference of MED value among people at different ages of different gender. The range of MED value to UVA was ≥30 J/cm2, and to UVB was ≥29. 1 mJ/cm2. Conclusion：MED of UV is probably related to the skin types, and UVA-MED, UVB-MED of the type Ill skin were signifi- cantly lower than type IV skin （P 〈0. 01 ）. Gender and age had no obvious impact on MED.