妊高征与新生儿缺氧缺血性脑病的临床检验指标分析

Pregnancy induced hypertension and neonatal hypoxic ischemic encephalopathy and clinical correlation analysis

目的：分析妊高征与新生儿缺氧缺血性脑病的临床相关性。方法选取我院2011年2月～2014年2月收治的429例孕妇为研究对象，根据高血压程度分为正常组351例，重度妊高征组16例，中度妊高征组28例，轻度妊高征组34例，比较各组新生儿缺氧缺血性脑病的发生情况。结果所有产妇都顺利分娩新生儿，重度妊高征围产儿死亡1例，新生儿缺氧缺血性脑病8例，中度妊高征患者新生儿缺氧缺血性脑病3例，轻度妊高征患者新生儿缺氧缺血性脑病3例，正常孕妇为1例。妊高征发病率15.4%，总发病率为3.0%，妊高征重度患者发生新生儿缺氧缺血性脑病的概率更高，中度次之，轻度最少，两两对比差异有统计学意义（P＜0.05）。结论妊高征产妇可使新生儿缺氧缺血性脑病发病率增加，早发现、早治疗妊高征，对于预防缺氧缺血性脑病的发生有重要意义。

Objective To analyze of relationship between pregnancy induced hypertension and neonatal hypoxic ischemic encephalopathy. Methods Selected from February 2011 to February 2014, 429 cases of pregnant women as the research object, according to the degree of hypertension 351 cases were divided into normal group, 16 cases of severe pih group and moderate pih group 28 cases, mild pih group of 34 cases, comparison between groups of neonatal hypoxic ischemic encephalopathy occurrence. Results All maternal birth of all newborns, severe pih perinatal death in 1 case, neonatal hypoxic ischemic encephalopathy in 8 cases, 3 cases of neonatal hypoxic ischemic encephalopathy （mild pih patients, 3 cases of neonatal hypoxic ischemic encephalopathy （mild pih patients and normal pregnant women in 1 case. Incidence of pih overall incidence of 3.0% 15.4%, the probability of neonatal hypoxic ischemic encephalopathy patients with seere pih in higher, moderate, mild, at least two contrast difference is obvious（P〈0.05）. Conclusion Pih women can increase the incidence of neonatal hypoxic ischemic encephalopathy, early detection, early treatment of pih, has important significance to preventing the occurrence of hypoxic ischemic encephalopathy.