天麻地黄钩藤汤联合卡托普利治疗阴虚阳亢型高血压随机平行对照研究

Gastrodia Elata Rehmannia Uncaria Soup with Enalapril Therapy Yin Deficiency Type Hand Hypertension Random Parallel Control Study

[目的]观察天麻地黄钩藤汤联合卡托普利治疗阴虚阳亢型高血压疗效。[方法]使用随机平行对照方法,将78例门诊患者按抽签法随机分为两组。注意饮食,忌烟酒、辛辣刺激食物,注意饮食卫生及规律。对照组39例卡托普利,12.5mg/次,3次/d。治疗组39例补虚泻实汤(干地黄、炒白芍、钩藤、丹参各15g,丹皮、菊花、女贞子、枸杞、天麻、罗布麻各12g,黄柏10g,知母8g),1剂/d,水煎200m L,早晚分服。连续治疗28d为1疗程。观测临床症状、证候改善率、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效30例,有效8例,无效1例,总有效率97.43%。对照组显效20例,有效12例,无效7例,总有效率82.05%。治疗组疗效优于对照组(P<0.05)。证候改善率治疗组优于对照组(P<0.05)。[结论]天麻地黄钩藤汤联合卡托普利治疗阴虚阳亢型高血压效果显著,值得推广。

[Objective]To observe the rhizoma gastrodiae rehmannia uncaria soup with enalapril therapy curative effect of Yin deficiency type hand high blood pressure. [Methods]Using random parallel control method, 78 cases of clinic patients were randomly divided into two groups according to the draw method. Pay attention to diet, avoid alcohol and tobacco, spicy stimulate food, pay attention to food hygiene and law. Control group 39 cases of captopril tablets, 12.5 mg/time, 3 times/d. Real soup or insufficiency of treatment group 39 cases（Gandihuang,Chaobaishao,Gouteng,Danshen each 15 g, Danpi,Juhua,Nvzhenzi,Gouqi,Tianma,Luobuma12 g, Huangbai 10 g,Zhimu 8 g）, 1/d, Fried 200 ml water, morning and evening dress. Continuous treatment of 28 d of 1 course of treatment. Observation of clinical symptoms, syndrome period, adverse reactions. As a course treatment, judge curative effect. [Results]The treatment group 30 cases had marked effect, 8 cases effectively, 1 had no effect, the total effective rate was 97.43%. Control group 20 cases had marked effect, 12 cases were effectively, 7 had no effect, the total effective rate was 82.05%. The treatment group curative effect is better than that of control group（P〈0.05）. Syndrome period treatment group is better than that of control group（P〈0.05）. [Conclusion] Gastrodia elata radix rehmanniae uncaria soup with enalapril therapy effect is remarkable, Yin deficiency type hand hypertension is worth promoting.