单侧低中频下降型突发性聋预后相关因素分析

Factors Affecting Prognosis in Unilateral Low-Middle Frequency Sudden Hearing Loss

目的：评估单侧低中频下降型突发性聋的相关因素对预后的影响。方法由2005~2013年入院的单侧低中频下降型突发性聋109例，均给以改善微循环加激素静点及其他对症治疗。患者按照性别、发病年龄、病程、听力损失程度、高频听力是否损伤、伴有糖尿病，高脂血症等因素分组，分析各因素与疗效（有效，无效）的相关性。先行单因素分析，可能影响疗效的因素再行logistic线性回归分析。结果在此次研究中，单侧低中频下降型突发性聋总有效率为73.4%（80/109），治愈率71.6%（78/109）。无效率为26.6%（29/109），患者性别、病程、听力损失程度、高频听力是否损伤、高脂血症，血粘稠度对疗效无明显影响；发病年龄和伴有糖尿病对疗效产生影响。结论年龄大于50岁、空腹血糖≥7.0mmol的单侧低中频下降型突发性聋患者疗效差。

Objective To investigate factors affecting unilateral low-middle frequency sudden hearing loss . Methods This is a retrospective analysis of 109 cases （109ears） of unilateral low-middle frequency sudden hearing loss from 2005 to 2013. Treatments included vasodilators and glucocorticoids. Cases were grouped based on gender, onset age, daration of dis？ease, degree of hearing loss, presence of high frequency hearing damage, comorbid diabetes mellitus, hyperlipidemia and oth？er factor. Correlations between these factors and treatment efficacy were studied using variable analysis followed by logistic linear regression analysis. Results In this study, the total effectiveness rate was 73.4%（80/109）. The rates of full recovery and no efficiency were 71.6%（78/109） and 26.6%（29/109）, respectively. Patients＇ gender, disease duration, degree of hear？ing loss, high frequency hearing impairment, hyperlipidemia, and blood viscosity had no obvious effects on treatment out？comes, whereas onset age and co-existing diabetes did. Conclusion Age over 50 years and glucose levels higher than 7.0 mol/l can negatively affect treatment outcomes in unilateral low-middel frequency sudden hearing loss.