妇科门诊泌尿生殖道支原体感染及药敏分析

Analysis of urogenital tract mycoplasma infection and drug sensitivity of reproductive system in gynecological clinic

目的:分析泌尿生殖道系统中支原体感染及药物敏感情况,指导临床合理用药。方法:用支原体培养及药敏试剂盒检测泌尿生殖道分泌物。结果:支原体检出阳性率为44.59%(305/684),其中Uu阳性百分率为69.51%(212/305),Mh阳性率为10.16%(31/305),两者混合感染阳性率为20.33%(62/305)。支原体对交沙霉素、强力霉素、克拉霉素较敏感,其敏感率>80%;对司帕沙星、氧氟沙星、左旋氧氟沙星、环丙沙星较不敏感,其敏感率<45%。结论:支原体感染以Uu为主,治疗以交沙霉素、强力霉素、克拉霉素为首选药物,临床还需根据支原体培养药敏结果个性化用药治疗。

Objective：To analyze the urogenital tract mycoplasma infection and drug sensitivity in order to provide guidiance for clinical rational drug use. Methods： Urogenital tract secretion was detected by myco- plasma culture and drug sensitivity kit. Results： The positive rate for mycoplasma was 44.59%（305/684） positive of Uu and Mh was 69.51%（212/305） and 10.16% （31/305）, respectively; the mixed infection by Uu and Mh was 20.33% （62/305）. The drug sensitivity test results showed that mycoplasma was more sensitive to clarithromycin,josamycin,doxycycline with the sensitive rate〉80%. It was less sensitive to ofloxacin, levofloxacin, sparfloxacin, ciprofloxacin, with the sensitivity rate〈45 %. Conclusion： Mycoplasma infection is mainly caused by Uu. Josamycin, doxycycline, and clarithromycin should be used mainly for treatment. The pratical treatment is advised to be based on the results of mycoplasma culture and drug sen- sitivity.