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性激素补充治疗对妇女乳腺密度的影响 被引量:4

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摘要 性激素补充治疗可有效改善妇女绝经相关症状,其与乳腺癌关系的纷争伴随着性激素补充疗法的始末。众多的专科医生、围绝经期和绝经后妇女对此问题也很关注和纠结。研究提示,乳腺密度(MD)与乳腺癌的危险性呈正相关,乳腺X线摄影是发现早期乳腺癌的重要方法,也是MD检测的最佳手段。MD受众多因素影响,本文将较常用的不同种类的性激素补充治疗药物对妇女MD的影响做一综述,供专科医生在临床工作中参考。
出处 《现代妇产科进展》 CSCD 2014年第12期994-997,共4页 Progress in Obstetrics and Gynecology
基金 国家自然科学基金项目(No:81302441)
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  • 1Kavanagh AM, Mitchell H, Giles GG. Hormone replace-ment therapy and accuracy of mammographic screening [ J ]. Lancet,2000,355 (9200) :270-274.
  • 2Kerlikowske K, Zhu W, Hubbard RA, eta/. Breast Cancer Surveillance Consortium. Outcomes of screening mammog- raphy by frequency, breast density, and postmenopausal hormone therapy[ J]. JAMA Intern Med,2013,173 (9) : 807-816.
  • 3Chiarellia M, Kirsh VA, Klar NS, et al. Influence of pat- terns of hormone replacement therapy use and mammo- graphic density on breast cancer detection [ J ]. Cancer Ep- idemiol Biomarkers Prey,2006,15 (10) :1856-1862.
  • 4Hou N, Hong S, Wang W, et al. Hormone replacement therapy and breast cancer: heterogeneous risks by race, weight, and breast density [ J ]. J Natl Cancer Inst, 2013, 105 ( 18 ) : 1365-1372.
  • 5Marchesoni D, Driul L, Ianni A, et al. Postmenopausal hor- mone therapy and mammographic breast density [ J ]. Ma- turitas ,2006,53 ( 1 ) :59-64.
  • 6Bruce D, Robinson J, McWilliams S, et ah Long-term effects of tibolone on mammographic density [ J ]. Fertil Steril,2004,82(5 ) : 1343-1347.
  • 7Lundstrom E, Hirschberg AL, Soderqvist G. Digitized as- sessment of mammographic breast density-effects of con- tinuous combined hormone therapy, tibolone and black co- hosh compared to placebo [ J ]. Maturitas, 2011,70 (4) : 361-364.
  • 8McTiernan A, Martin CF, Peck JD, et al. Estrogen plus progestin use and mammographic density in postmenopa- usa/women:Women's Health Initiative Randomized Trial [ J ]. J Natl Cancer Inst,2005,97 (18) : 1366-1376.
  • 9MeTiernan A, Chlebowski RT, Martin C, et al. Conjugated equine estrogen influence on mammographic density in postmenopausal women in the Women's Health Initiative Randomized Trial [ J ]. J Clin Oneol, 2009,27 ( 36 ) : 6135- 6143.
  • 10Crandall C J, Aragaki AK, Cauley JA, et al. Breast tender- ness after initiation of conjugated equine estrogens and mammographic density change [ J ]. Breast Cancer Res Treat, 2012,131 ( 3 ) : 969 -979.

同被引文献51

  • 1黄平,周宏灏.雌激素合成及代谢酶与乳腺癌易感性的研究[J].肿瘤学杂志,2004,10(4):267-270. 被引量:6
  • 2Santen RJ,Allred DC,Ardoin SP,et al.Postmenopausal hormone therapy:an Endocrine Society scientific statement[J].J Clin Endocrinol Metab,2010,95(7Suppl 1):s1-s66.
  • 3Collins A,Politopoulos I.The genetics of breast cancer:risk factors for disease[J].Appl Clin Genet,2011,4:11-19.
  • 4Petz LN,Ziegler YS,Schultz JR,et al.Differential regulation of the human progesterone receptor gene through an estrogen response element half site and Sp 1sites[J].J Steroid Biochem Mol Biol,2004,88(2):113-122.
  • 5Mc Tiernan A,Martin CF,Peck JD,et al.Estrogen-plusprogestin use and mammographic density in postmenopausal women:Women's Health Initiative randomized trial[J].J Natl Cancer Inst,2005,97(18):1366-1376.
  • 6Rossouw JE,Anderson GL,Prentice RL,et al.Risks and benefits of estrogen plus progestin in healthy postmenopausal women:principal results from the Women's Health Initiative randomized controlled trial[J].JAMA,2002,288(3):321-333.
  • 7de Villiers TJ,Pines A,Panay N,et al.Updated 20131nternational Menopause Society recommendations on menopausal hormone therapy and preventive strategies for midlife health[J].Climacteric,2013,16(3):316-337.
  • 8Chen CL,Weiss NS,Newcomb P,et al.Hormone replacement therapy in relation to breast cancer[J].JAMA,2002,287(6):734-741.
  • 9Stahlberg C,Pedersen AT,Lynge E,et al.Hormone replacement therapy and risk of breast Cancer:the role of progestins[J].Acta Obstet Gynecol Scand,2003,82(7):335-344.
  • 10Beral V,Million Women Study Collaborators.Breast cancer and hormone-replacement therapy in the Million Women Study[J].Lancet,2003,362(9382):419-427.

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