一期多平面微创手术治疗轻中度睡眠呼吸暂停低通气综合征35例

Minimally invasive one-stage multilevel treatment for mild and moderate obstructive sleep apnea hypopnea syndrome in 35 patients

目的探索一期多平面微创手术治疗轻中度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的可行性和临床效果。方法回顾性分析35例行一期多平面微创手术治疗轻中度OSAHS患者的临床资料,并进行统计学处理分析。结果治愈8例(22.9%),显效22例(62.7%),有效5例(14.3%),无效0例。平均呼吸暂停低通气指数(AHI)术前(18.6±7.5)、术后(8.0±3.3),差异有统计学意义;平均最低血氧饱和度(LSaO2)术前(78.4±6.1)%、术后(84.4±5.2)%,差异有统计学意义;平均Epworth嗜睡量表(ESS)评分术前(11.6±2.5)、术后(7.7±2.4),差异有统计学意义。主观症状均明显改善,术后1个月随访未出现反流、吞咽困难等症状。结论一期多平面微创手术后患者AHI、LSaO2及ESS指标均改善明显,一期多平面微创手术可以作为轻中度OSAHS患者治疗的一种选择。

Objective To explore safety and efficacy of minimally invasive one-stage multilevel treatment for mild and moderate obstructive sleep apnea hypopnea syndrome.Methods Clinical data of 35 cases of mild and moderate OSAHS underwent minimally invasive one-stage multilevel treatment,from January 201 1 to June 2013 in Department of Otorhinolaryngology and Head ＆amp;Neck Surgery,were reviewed.Results Minimally invasive one-stage multilevel treatment improved the sleep and daytime symptoms related to OSAHS.After at least 6 months of follow-up,there were eight cured（22.9%）,twenty-two improved markedly （62.7%）,five effective（14.3%）without invalid case.The average apnea-hypopnea index was decreased from 18.6 to 8.0 （P〈0.05）;The mean of lowest oxygen saturation was increased from 78.4% to 84.4% （P〈0.05）and the average Epworth sleepiness scale score was decreased from 11.6 to 7.7 （P〈0.05）.Also,there was significant improvement in snoring,daytime sleepiness,and overall impact of the disease on quality of life.All patients returned to normal swallowing one month after the surgeries.Conclusion AHI, LSaO2 and ESS are significantly improved in OSAHS patients treated with minimally invasive one-stage multilevel treat-ment.The procedure is recommended for mild and moderate OSAHS.