生态因子对药用植物次生代谢物的影响及其研究方法

The Effcts of ecological factors on the secondary metabolites in medicinal plants and their research methods

概述了生态环境因子对药用植物次生代谢物合成积累的影响,并阐述了植物生态学、功能基因组学、蛋白质组学、代谢组学及系统生物学方法在药用植物次生代谢物研究中的应用。指出应加强多生态因子综合作用的系统研究;系统整合多种组学技术,深入研究药用植物次生代谢物的生物合成途径、代谢规律及关键调控位点,从而为系统阐释药用植物有效成分成因和药材品质形成机制、代谢产生药用植物活性成分以及建立药材优质生产基地提供科学依据。

The paper summarizes the effects of ecological factors on the accumulation of secondary metabolites synthesis in me- dicinal plants. Plant ecology, functional genomics, proteomics, metabolomics and systems biology are expounded in the study of the secondary metabolites in medicinal plants. The paper points out a systematic study of the combined action of many ecological factors sbould be strengthened, integrates a variety of omics technology by the numbers, studies the biosynthetic pathways of sec- ondary metabolites, the law of plant metabolism and key control site in - depth, thus provides a scientific basis for interpretation active ingredients of medicinal plants and medicinal materials quality formation mechanism, actives ingredients of medicinal plant metabolism and high quality of Chinese herbal medicine production base.