摘要
[目的]研究香烟烟蒂水浸泡液对家兔离体小肠收缩运动的影响。[方法]采用常规离体灌注小肠平滑肌标本活动的试验方法,应用3种不同剂量(0.2、0.4、0.8 ml)的烟蒂水浸泡液作用于离体肠段,观察用药前后的离体肠段收缩幅度和收缩频率的变化。[结果]对离体肠段的收缩幅度,低剂量组有显著性差异(P<0.05):中、高剂量组均有高度显著性差异(P<0.01):对离体肠段的收缩频率,低剂量组差异显著(P<0.05)中、高剂量组差异极显著(P<0.01)。[结论]香烟烟蒂水浸泡液能增大家兔离体小肠的收缩幅度,减弱收缩频率,作用机理可能与钠离子和钙离子的转运有关。
[ Objective ] To investigate the effects of cigarette end immersion on contraction of rabbit small intestine in vitro. [ Method ] The routine experimental method of small intestinal smooth muscle isolated from rabbits is used. Three different doses (0.2, 0.4, 0. 8 ml) cigarette end immersion was added into isolated small intestine. The contraction amptitude and the frenquency of the contraction changes were re- corded. [ Result ] On contraction amplitude, the low-dose group were significant difference ( P 〈 0. 05 ) ; high dose group was highly significant difference( P 〈 0.01 ) ; On contraction frequency, the low-dose group were significant difference( P 〈 0.05 ) ; high dose group was highly significant difference(P 〈0. O1 ). [ Conclusion] Cigarette end immersion can increase intestinal contraction, abate frequency, the mechanism may be associated with the transport of sodium and calcium ions.
出处
《安徽农业科学》
CAS
2015年第5期129-130,158,共3页
Journal of Anhui Agricultural Sciences
基金
国家大学生创新训练计划项目(201410757025)
关键词
香烟
离体小肠
收缩活动
Cigarette
Isolated small intestine
Contraction