儿童哮喘发病的相关因素分析

Analysis on related factors of onset of childhood asthma

目的:对导致儿童哮喘的危险因素进行分析,以有效地指导临床治疗。方法:将82例哮喘儿童及40例健康儿童作为观察对象,以哮喘儿童为哮喘组,以健康儿童为健康组,回顾性分析两组的临床资料,对比两组间临床资料的差异,并通过对比两组间临床资料以总结导致患儿发生哮喘的危险因素。结果:两组间性别、年龄、出生时体重、初次使用抗生素年龄比较无统计学差异(P>0.05);而两组药物过敏史、喂养方式、1岁内抗生素使用次数、饲养宠物、种植花草及居住环境均存在统计学差异(P<0.05)。经单因素及Logistic回归分析显示:存在药物过敏史、非母乳喂养、1岁内抗生素使用>3次、饲养宠物、种植花草及居住平房均为导致儿童发生哮喘的危险因素(P<0.05)。结论:临床多种危险因素均可导致儿童哮喘疾病的发生,临床应注意以上危险因素的控制。

Objective： To analyze the risk factors of childhood asthma,effectively guide clinical treatment. Methods： Eighty-two children with asthma and forty healthy children were selected as asthma group and control group,respectively; the clinical data of all the children were analyzed retrospectively,and the differences were compared,the risk factors of asthma in children were summarized. Results：There was no statistically significant difference in gender,age,birth weight and the age of applying antibiotics for the first time between the two groups（ P〉0. 05）; but there were statistically significant differences in the history of drug sensitivity,feeding patterns,the times of applying antibiotics with one year after birth,keeping pets,planting flowers and plants,living environment between the two groups（ P〈0. 05）. Univariate logistic regression analysis showed that the history of drug sensitivity,artificial feeding,the times of applying antibiotics with one year after birth 〉3,keeping pets,planting flowers and plants,living in bungalow were risk factors of asthma in children（ P〈0. 05）. Conclusion： A variety of clinical risk factors may lead to childhood asthma,the risk factors above- mentioned should be paid more attention to and controlled.