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结肠癌术中失血对长期生存影响的重要性

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摘要 目的:本研究验证了结肠癌术中失血量影响患者长期生存这一假说。背景:结直肠癌术中失血与并发症发生及早期死亡率相关。方法:我们记录了我院所有在2000年-2007年间接受结肠癌手术患者的临床资料。分析了临床Ⅰ-Ⅲ期接受根治性手术患者的数据。术后6个月内死亡的患者予以排除。用单因素及多因素Cox比例风险回归方法计算风险比值。由于相关变异,失血量、输血及并发症发生在单独的多因素分析中检验。结果:在单因素及多因素分析中,术中失血量达到或超过250ml、男性、发生并发症、年龄〉75岁及临床Ⅲ期为总体死亡率的危险因素。围手术期输血只在单因素分析中证明为危险因素。结论:本研究结果支持结肠癌术中失血量影响患者长期生存这一假说。
作者 崔凯 赵宇
出处 《中国伤残医学》 2015年第4期72-74,共3页 Chinese Journal of Trauma and Disability Medicine
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