2747例感音神经性聋内耳畸形分类的研究

Study on 2 747 cases of inner ear malformation for its classification in patient with sensorineural hearingloss

目的:研究大宗病例高分辨率CT资料,了解中国人感音神经性聋患者群体内耳畸形的发病情况,探讨内耳畸形分类的依据。方法:对2 747例感音神经性聋患者的资料进行回顾性分析,按照Sennaroglu分类方法对患者的内耳CT检查结果进行分类研究。结果:1发现内耳畸形843例(30.69%);2843例内耳畸形中耳蜗畸形占52.31%(441/843),单纯前庭导水管畸形占40.33%(340/843),单纯前庭/半规管/内耳道畸形占7.35%(62/843);3441例耳蜗畸形中Michel畸形占1.13%(5/441),耳蜗未发育占1.81%(8/441),共同腔畸形占3.17%(14/441),IP-Ⅰ畸形占8.62%(38/441),耳蜗发育不全占9.07%(40/441),Mondini畸形(伴大前庭水管)占76.19%(336/441)。结论:通过高分辨率CT检查发现中国人感音神经性聋患者群体中存在较高的内耳畸形发病率,Sennaroglu分类方法对于各类内耳畸形发病率的流行病学统计具有重要的指导意义。

Objective：Analyze the data of the patients with sensorineural hearing loss in China and study the classification and incidence of inner ear malformationsby the high-resolution computed, tomography. Method： The investigation took a retrospective review of CT findings relating to the 2 747 cases of outpatients. The inner ear malformations diagnosed by CT were classified according to the methods proposed by Sennaroglu. Result：（1）843 cases of inner ear malformations were found in 2 747 cases of patients with sensorineural hearing loss by CT examination. The incidence of inner ear malformation was 30.69 % （843/2 747）. （2）The epidemiological information of 843 cases of inner ear malformation according to Sennaroglu＇s classification was as follows： cochlea was 52.31 % （441/ 843）, simple vestibular aqueduct was 40.33% （340/843）, simple vestibular/ semicircular canal/ internal auditory canal were 7.35%（62/843） of the group. （3）441 cases of cochlea malformation were consisted of these types of malformation： Michel deformity was 1.13%（5/441）, cochlear aplasia was 1.81%（8/441）, common cavity deformity was 3.17%（14/441）, incomplete partition type I was 8.62%（38/441）, cochlea hypoplasia was 9.07% （40/441） and incomplete partition type Ⅱ was 76. 19%（336/441） of the group. Conclusion：The results suggested that 30.69% cases of inner ear malformation can be found in patients with sensorineural hearing loss, which is more higher than reported by the high-resolution computed tomography. Sennaroglu＇s classification is instructively significant in investigating the status of inner ear malformations.