自体血回输应用于严重创伤的研究进展

Research progress of autologous blood transfusion in major trauma

背景每年全球死于严重创伤的人数高达上百万人。严重创伤后的大出血不仅是常见致死原因，而且是住院早期死亡的首要原因。常见及首要的处理就是输注大量血液成分。目的对不同严重创伤手术中自体血回收后的血液成分进行分析，为临床上自体血回输（autotransfusion，AT）的合理运用提供参考。内容介绍AT的发展历史及目前使用情况，回顾国内外相关研究，对不同部位创伤应用AT治疗后的血液成分进行分析，探讨其对红细胞功能、炎症反应、凝血功能的影响，简述近期研究热点。趋向AT能缓解用血紧张的情况，且随着对其深入研究，患者将获得更大的临床效益。

Background Millions of people die from major trauma each year. Massive hemorrhage after major trauma is not only a common cause of death, but also the leading cause of death in early hospitalization. The common and primary management of these critical conditions is blood component infusion. Objective Blood components were analyzed after autologous transfusion（AT） in various kinds of acute traumatic surgeries, to provides reference basis for applying rationally in the clinical autologous blood transfusion. Content A brief introduction of AT history and its current usewere reviewed？in different kinds of？trauma, the blood components after AT were analyzed to investigate the erythrocyte function, inflammation, coagulation function and hot point of researching. Trend AT can partly solve the situation of blood shortage, the better understanding of AT, the greater clinical benefits we can achieve.