组织工程肺支架的选择

The choice of the lung scaffold in tissue engineering

背景肺移植手术在终末期肺疾病的有效治疗中已被广泛接受，但供源短缺、免疫抑制、潜在疾病传播等现象日益突出，组织工程肺的构建和应用有望解决以上难题。目的总结组织工程肺支架的研究进展。内容就组织工程肺支架的性能、材料、制备和展望等方面进行综述。趋向为终末期肺疾病的治疗提供新思路。

Background End-stage pulmonary disease is one of the major heahhcare challenges in the world, and lung transplantation is the only choice for survival. Yet, the donor organ shortage, needed and infective transmission limit the application of lung transplantation. The engineered lung tissue could theoretically overcome these hurdles. Objective This review will discuss recent advances of scaffolds in the tissue engineering. Content Narrating the scaffold of the lung in tissue engineering from performance, materials, preparation and prospect. Trend to provide new ideas and method for thetreatment on the therapy of end- stage lung diseases.