地佐辛用于术后硬膜外镇痛的效果比较

Comparison of Effect of Dezocine in Epidural Analgesia after Operation

目的:比较并分析地佐辛用于术后硬膜外镇痛的效果和安全性。方法:选取本院自2013年8月-2014年2月收治的行腹部手术的患者60例,采用随机数字表法将其分为两组,每组各30例,对照组采用吗啡进行术后硬膜外镇痛,试验组采用地佐辛进行术后硬膜外镇痛,对比经过镇痛后,对患者的VAS评分和不良发应进行比较。结果:试验组与对照组各时间段镇痛效果相当,两组比较差异无统计学意义。试验组不良反应发生率6.7%,对照组不良反应发生率56.7%,两组比较差异有统计学意义(P<0.05)。结论:采用地佐辛进行术后硬膜外镇痛的镇痛效果良好,不良反应发生率低,值得在临床上推广应用。

Objective：To compare and analyze the efficacy and safty of Dezocine in epidural analgesia after operation.Method：60 patients who operated abdominal surgery in our hospital from August 2013 to February 2014 were enrolled in this study.They were randomly divided into control group and experiment group,30 patients in each group.The patients in control group were treated with morphine, and the patients in experiment group were treated with dezocine.The VAS score and adverse reactions were compared between two groups after analgesia.Result：There were no significant difference in analgesia effect of all the time between experiment group and control group.The incidence of adverse reactions were lower in experiment group of 6.7% than in control group of 56.7%,the difference was statistically significant（P〈0.05）.Conclusion：The effect of Dezocine in epidural analgesia after operation is good, the incidence of adverse reactions is low, and it is worthy of further widespread application in clinic.