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PD-1/PD-L1信号通路在妊娠中的研究进展 被引量：6

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摘要 程序性细胞死亡受体1（Programmed cell death1,PD-1）及其配体（PD-L1和PD-L2）介导的信号通路在调控机体免疫稳态,尤其是T细胞免疫应答和T细胞免疫稳态中发挥重要作用。研究表明,PD-1/PD-L1信号通路除参与自身免疫、慢性感染性疾病、移植排斥和肿瘤免疫逃逸之外,还参与母胎免疫耐受的诱导和妊娠的维持。
作者 张永红 廖爱华
机构地区 华中科技大学同济医学院计划生育研究所/生殖医学中心
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2015年第1期126-130,共5页 Chinese Journal of Immunology
基金 国家自然科学基金资助项目(No.81070507和No.81471415)
关键词 信号通路 妊娠 T细胞免疫应答 慢性感染性疾病 肿瘤免疫逃逸 母胎免疫耐受 免疫稳态 死亡受体
分类号 R392 [医药卫生—免疫学]
  • 相关文献

参考文献28

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共引文献6

同被引文献61

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引证文献6

二级引证文献34

中国免疫学杂志
2015年 第1期

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