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地佐辛联合帕瑞昔布钠用于腹腔镜阑尾切除术后镇痛效果的观察 被引量:6

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摘要 目的观察与评价地佐辛联合帕瑞昔布钠对腹腔镜阑尾切除术患者术后镇痛效果的影响。方法40例ASAⅠ或Ⅱ级行择期腹腔镜阑尾切除术患者,采用完全随机分组方法分为帕瑞昔布钠组(Ⅰ组)和地佐辛+帕瑞昔布钠组(Ⅱ组),帕瑞昔布钠40mg于术前15min静脉注射,地佐辛5mg于术毕前30min静脉注射。分别记录术后2h(T1)、4h(T2)、8h(T3)、12h(T4)及24h(T5)不同时点患者的VAS评分及恶心、呕吐等不良反应的发生率。结果术后T1、T2、T3时点VAS评分,Ⅱ组低于Ⅰ组,差异均有统计学意义(P〈0.05);两组患者术后呼吸抑制,恶心呕吐等不良反应发生率比较,差异无统计学意义(P〉0.05)。结论与单独应用帕瑞昔布钠术后镇痛相比,地佐辛联合帕瑞昔布钠对腹腔镜阑尾切除术患者的术后镇痛效果更确切、完善,其不良反应发生率无差异。
作者 郑雪珍
出处 《浙江临床医学》 2015年第1期132-133,共2页 Zhejiang Clinical Medical Journal
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