摘要
滑膜间充质干细胞(Synovium-derived mesenchymal stem cells,SMCSs)的增殖能力强,分离方法简便,具有多向分化潜能。其中SMSCs的成软骨分化能力尤为突出,被广泛应用于软骨缺损修复的实验中,因此SMSCs可能成为软骨组织工程领域中新的种子细胞,为关节软骨疾病治疗提供了新的可能性。本文对SMSCs的组织来源、生物学特性以及在软骨组织工程中的应用展开综述。
Besides the general multipotency in common with other MSCs,synovium-derived mesenchymal stem cells exhibit easy access to cell resources and higher ability of proliferation and superiority in chondrogenesis.Under appropriate culture conditions,SMSCs were induced to differentiate into chondrocyte,osteocyte,and adipocyte lineages.This provides a new MSC-based therapeutic strategy for the repair of cartilage injury.This article expands overview of the tissue origin,biological characteristics of SMSCs and application in cartilage tissue engineering.
出处
《海南医学》
CAS
2015年第2期214-217,共4页
Hainan Medical Journal
关键词
滑膜间充质干细胞
种子细胞
软骨组织工程
Synovium-derived mesenchymal stem cells
Seed cell
Cartilage tissue engineering