枸橼酸咖啡因治疗早产儿原发性呼吸暂停临床观察与护理

The Clinical Observation and Nursing of Caffeine Citrate in the Treatment of Premature Infants with Primary Apnea

目的:探讨枸橼酸咖啡因治疗早产儿原发性呼吸暂停的临床疗效和护理措施。方法:对42例早产儿原发性呼吸暂停患儿给予枸橼酸咖啡因规范治疗,并进行实时观察和规范护理。结果:枸橼酸咖啡因治疗早产儿原发性呼吸暂停后,患儿呼吸暂停平均每天发作次数明显减少、严重程度明显降低(P均<0.01),其中32例(76.19%)呼吸暂停发作减少或消失,7例(16.67%)仍频繁发作需呼吸机辅助通气,2例(4.76%)因其他并发症抢救无效而死亡,1例(2.38%)因经济原因放弃治疗。观察护理重点为:(1)规范用药时间,合理配置药物,严格控制输液速度;(2)用药过程中注意心率、呼吸、尿量、血压的监护;(3)合理喂养,预防感染。结论:对枸橼酸咖啡因治疗的早产儿原发性呼吸暂停患儿进行实时观察和规范护理,可获得较好的临床效果。

Objective： To investigate the clinical observation and nursing measures of caffeine citrate in the treatment of primary apnea in preterm infants. Methods： Forty-two cases of preterm infants with primary apnea were given caffeine citrate normalization treatments and the real-time observations, standardized nursing cares. Results： After treatment, the times of apnea episodes every day was significantly decreased and the severity of disease was improved （P〈0.01）. The times of apnea episodes in 32 cases （76. 19% ） reduced or disappeared, 7 cases （ 16.67% ） were still given respirator assisted ventilation, 2 cases （4.76%） were death, 1 case （2. 38% ） gave up treatment for economic reasons. The duration and the rational allocation of drugs, controlling the speed of infusion was the first nursing element. Pay attention to the monitoring of heart rate, breathing, urine volume, blood pressure, which was the second nursing element. Reasonable feed, infection prevention was the third nursing element. Conclusion： Caffeine citrate has clinical efficacy on the children with primary apnea premature, and can obtain good clinical effect.