超声评估动脉中内皮功能价值及其与动脉硬化的关系分析

Ultrasound Assessment of the Artery Endothelial Function Value and Analysis on the Relationship with Atherosclerosis

目的:探讨超声评估动脉中内皮功能价值及其与动脉硬化的关系。方法:选取43例本院2008年3月-2012年8月确诊治疗的冠状动脉粥样硬化性心脏病(冠心病)患者作为动脉硬化组,同期选取体检科正常成年人43例作为对照组,采用彩色多普勒超声进行动脉中内皮功能各项参数检测,采用Logistic回归分析法分析内皮功能与动脉硬化的关系。结果:动脉硬化组患者颈动脉总斑块发生率、动脉内-中膜厚度显著高于对照组,比较差异有统计学意义(P<0.05);动脉硬化组患者内皮舒张能力明显低于对照组患者,比较差异有统计学意义(P<0.05);Logistic回归分析法结果显示,颈动脉中斑块、内-中膜厚度、内皮舒张能力是冠状动脉粥样硬化的危险因素。结论:超声检测能有效评估动脉内皮功能,颈动脉中斑块、内-中膜厚度、内皮舒张能力与动脉硬化有密切关系,可作为临床预防及诊断动脉硬化的重要指标。

Objective： To discuss Ultrasound assessment of the artery endothelial function value and analyze the relationship with atherosclerosis. Method： 43 patients with coronary heart disease were selected from March 2008 to August 2012 in our Hospital as atherosclerosis group, at the same time to choose a medical section 43 cases normal adults as control group, all the patients received color Doppler ultrasound to arterial endothelial function in each parameter detection, to analyze the relationship endothelial function and the hardening of the arteries by Logistic Regression Analysis. Result： Atherosclerosis group with carotid artery plaque incidence, carotid artery, carotid artery- in the film thickness was significantly higher than the control group, the difference was statistically significant（P〈0.05）. Atherosclerosis group endothelial diastolic ability significantly was lower than the control group patients（P〈0.05）. Logistic regression analysis results showed that, carotid of plaques, carotid artery-in the film thickness, endothelial diastolic ability was a risk factor for coronary atherosclerosis. Conclusion： Ultrasonic testing can effectively assess artery endothelial function, carotid of plaques, carotid artery-in the film thickness, endothelial diastolic ability has close relationship with coronary atherosclerosis, it＇s expected to become the index of prognosis of atherosclerosis.