甲状舌管癌的临床特征

Clinical features of thyroglossal duct carcinoma

目的:总结甲状舌管癌的临床特征及治疗方法。方法:回顾性分析北京协和医院收治的160例甲状舌管病变患者的临床资料,并检索相关文献。结果:160例患者中,甲状舌管癌3例(1.88%)。3例均采取手术治疗彻底切除病变,术后病理确诊为甲状舌管乳头状癌。其中1例伴有颈部淋巴结肿大,同期行颈淋巴清扫术并证实为转移癌,术后采用I131治疗。分别随访2、10和14年未见复发或转移。结论:甲状舌管癌发病率极低,诊断需通过病理检查明确,治疗原则首选手术切除,必要时同期行颈淋巴清扫术。

Objective：To analyze the clinicopathological features, treatments, and prognosis of patients with papillary TDCa. Method：A retrospective study was conducted of the medical records of our hospital for cases of TDCa. General clinical information including diagnostic criteria and treatments was obtained and analyzed. A liter- ature review was also conducted. Result： There were 160 cases of thyroglossal duct anomalies hospitalized in Pe- king Union Medical College Hospital in the past 20 years, and TDCa was diagnosed in 3 （1.88%） cases. All 3 ca- ses underwent local radical resections, and papillary TDCa was diagnosed based on the pathology examination. Se- lective neck dissection was chosen in one which was confirmed with cervical lymphatic metastasis. All patients were followed up with no recurrences or metastasis. Conclusion.. The incidence of TDCa is very low and the pathol- ogy examination is the only way to confirm the diagnosis. Surgery, especially Sistrunkrs procedure, is the treat- ment of choice, with low complications and recurrence. In the presence of cervical lymphadenopathy, selective neck dissection should be considered.