自觉听力正常的后循环缺血患者纯音听阈与耳声发射结果分析

Pure tone thresholds and Otoacoustic Emissions in PCI Patients without Hearing Loss Complaints

目的：探讨自觉听力正常的后循环缺血（posterior circulation ischemia ，PCI）患者的纯音测听和耳声发射的结果及临床意义。方法选择经临床确诊为PCI且自觉听力正常的患者40例（80耳）作为实验组，健康成年人30例（60耳）作为对照组，两组均行纯音测听、瞬态诱发耳声发射（TEOAE）和畸变产物耳声发射（DPOAE）检查，对结果进行统计学分析。结果 PCI组125～8000 Hz各频率气导听阈与对照组比较差异无统计学意义（ P＞0．05）；PCI组的TEOAE检出率（47．5％，38／80）低于对照组（95．0％，57／60），差异有统计学意义（P＜0．01）；PCI组DPOAE各频率检出率、幅值均低于健康对照组（P＜0．05），尤以高频区明显（P＜0．01）。结论后循环缺血可以影响耳蜗的血液供应，导致常规纯音测听难以发现的耳蜗功能损害，尤以高频区明显。

Objective To study the audiometry and otoacoustic emissions in patients with posterior circulation ischemia（PCI） .Methods Forty patients treated by neurologists were selected as the experimental group who re_ceived pure tone audiometry ,tympanometry ,otoacoustic emissions （OAE） and distortion products otoacoustic emis_sions （DPOAE） examinations .Thirty healthy objects were chosen as the control group .The data from the PCI groups and the control group were compared using the SPSS 14 .0 software .ResuIts The difference in pure tone thresholds across 125 to 8 000 Hz between the PCI group and the control group was not statistically significant （P〉0 .05） .In the PCI patients ,the prevalence of TEOAE was only 47 .5% ,significantly different from that of in the control group .The prevalence of DPOAE at 0 .5～8 kHz were between 57 .9% ～77 .6% in PCI patients ,and the amplitudes of DPOAE were reduced significantly （P〈0 .05） .ConcIusion Cochlear damages can occur to patients with PCI ,especially in the high frequency range .These results suggest that OAE can be used as an important diag_nostic test for patients with PCI ,and might be helpful for the location diagnosis of PCI .