126例绝经前妇女冠心病的危险因素调查分析

Risk Factors Investigation and Analysis of 126 Premenopausal Women with Coronary Heart Disease

目的分析绝经前妇女冠心病的危险因素。方法选择我院2010年5月至2013年12月间收治的126例绝经前冠心病患者为观察组,所有患者均经冠脉造影检查确诊,另选取同期来我院体检的126例非冠心病者为对照组,抽血检测两组人群的生化指标,同时详细询问两组人群的病史情况。结果观察组患者的BMI显著高于对照组,两组人群在高血压史和糖尿病史之间的差异有统计学意义(P<0.05),吸烟史和家族史的组间差异无统计学意义(P>0.05)。观察组患者的TG、UA、CRP以及HCY水平明显高于对照组,而HDL水平低于对照组,组间差异有统计学意义(P<0.05),两组间在TC、LDL方面的差异无统计学意义(P>0.05)。结论高血压、糖尿病及血脂水平异常是绝经前妇女冠心病的危险因素,临床应警惕高危因素,关注高危人群,尽早干预。

Objective To analyze the risk factors of coronary heart disease in premenopausal women.Methods 126 premenopausal women with coronary heart disease in our hospital were selected as observation group, the other 126 cases with non coronary heart disease were selected as control group, detected biochemical indexes of blood and asked for details of the history.Results BMI of cases in observation group was signiifcantly higher than that in control group, the difference of history of hypertension and diabetes history between two groups has statistical significance（P＆lt;0.05）, there was no significant difference in smoking history and family history group （P＆gt;0.05）. TG, UA, CRP and HCY levels of cases in observation group were signiifcantly higher than those in control group, while the HDL level lower than control group, there was signiifcant difference between two groups（P＆lt;0.05）, there was no signiifcant difference of TC, LDL between two groups（P＆gt;0.05）.Conclusion Hypertension, diabetes and lipid abnormalities are risk factors of coronary heart disease in premenopausal women, should guard against the risk factors, take attention to high-risk groups, and take intervention early.