老年初诊2型糖尿病患者两种降糖方案的临床疗效观察

Clinical Curative Effect Observation of Two Kinds of Hypoglycemic Program Treat Elderly Type 2 Diabetes

目的对比老年初诊2型糖尿病口服降糖药与注射胰岛素强化2周后改口服降糖药治疗2型糖尿病的效果差异分析。方法选取我院2011年5月至2012年5月期间初次确诊为2型糖尿病的老年患者,共计100例,将其分为实验组、研究组(每组各50例)。其中实验组为口服降糖药物患者,研究组为通过胰岛素强化2周后改口服降糖药治疗患者。然后对比两组患者在治疗前后的血糖变化情况及低血糖发生率。结果两组患者通过积极地配合治疗,其血糖均控制在良好范围,研究组患者在接受胰岛素强化治疗2周后的效果要高于实验组。结论口服降糖药与注射胰岛素强化2周后改口服降糖药治疗2型糖尿病均有显著效果,但注射胰岛素强化2周后改口服降糖药治疗的患者血糖控制情况要高于单纯口服降糖药物的患者,且服用降糖药物的患者出现的不良反应要高于注射胰岛素治疗的患者。

Objective To analyze the difference after 2 weeks of oral hypoglyeemic drugs for treating type 2 diabetes compared with elderly type 2 diabetes oral antidiabetie drugs and injection of insulin. Methods In our hospital fxom May 2011 to May 2012 during the first-time diagnosed elderly patients with type 2 diabetes mellitus, a total of 100 cases, divided into the experimental group, the study group （n=50）. The experimental group for oral hypoglycemic agents, patients, study group by intensive insulin after 2 weeks of oral hypoglycemic drugs in treating patients with modified. Then the two groups were compared in the changes of blood glucose and the incidence of hypoglycemia before and after treatment. Results Two patients by actively cooperate with the treatment, the blood glucose was controlled within a good range, the patients in the observation group received intensive insulin after 2 weeks of treatment effect than the experimental group. Conclusion Oral antidiabetic drugs and injection of insulin in 2 weeks after the oral hypoglycemic drugs in treating type 2 diabetes has remarkable effect, but the injection of insulin intensive control of blood glucose in patients with 2 weeks a^r oral hypoglyeemic therapy than simple oral hypoglycemic agents, patients, and taking the adverse reaction of hypoglycemic drugs in patients was higher than that of insulin injection treated patients.