大柴胡汤加减治疗慢性胆囊炎临床研究

Clinical Study on Modified Dachaihu Tang Treatment of Chronic Cholecystitis

目的:探讨大柴胡汤加减联合茴三硫胶囊治疗慢性胆囊炎的临床疗效。方法:将120例慢性胆囊炎患者随机分成两组各60例。对照组给予单纯茴三硫胶囊来治疗,每次25 mg,每日3次。治疗组在对照组的基础上给予大柴胡汤随证加减,每日1剂。两组疗程均为1个月。治疗前后对患者胸胁胀痛,心下痞满,纳差进行中医症状评分;彩超检测胆囊壁的厚度、毛糙及胆汁透声变化,判断影像学及综合疗效。结果:治疗组影像学有效率95.00%,对照组影像学有效率为78.33%,两组比较差异有统计学意义(P<0.05);治疗组综合有效率95.00%,对照组综合有效率75.00%,两组比较,差异有统计学意义(P<0.05);治疗组中医症状积分明显低于对照组(P<0.05)。结论:大柴胡汤加减联合茴三硫胶囊治疗慢性胆囊炎可明显改善症状,疗效确切。

Objective：To investigate the clinical effect of Dachaihu Tang combined with Anethol Trithione Capsules in the treatment of chronic cholecystitis. Methods：120 cases of chronic cholecystitis were randomly divided into two groups of 60 cases. The control group was given only Anethol Trithione Capsules,25 mg each time,3 times a day. The treatment group was treated with modified Dachaihu Tang based on the control group. Two groups were treated for 1 month. Observed scores of symptoms of Chinese medicine,such as chest and hypochondrium distending pain,epigastric painful abdominal mass,poor appetite before and after treatment;thickness,coarse and a- coustic changes of bile by color Doppler ultrasound,and judged iconography and comprehensive efficacy. Results：The imaging efficiency of treatment group was 95. 00%,and the control group was 78. 33%,there was significant difference between two groups（P﹤0. 05）;Comprehensive efficiency of treatment group was 95. 00%,and the control group was 75. 00%（P﹤0. 05）;TCM symptom score of the treatment group was significantly lower than the control group（P﹤0. 05）. Conclusion：Modified Dachaihu Tang combined with Anethol Trithione Capsules treatment of chronic cholecystitis can obviously improve the symptoms of patients,and obtain definite curative effect. Reference citation：SHI Qingjie. Clinical Study on Modified Dachaihu Tang Treatment of Chronic Cholecystitis[ J]. China Journal of Chinese Medicine,2015,30（2）：287-288,291.