妊娠晚期凝血功能指标和血小板监测的临床意义

The Clinical Significance of Coagulation Indicators and Platelet Parameters in Late Pregnant

目的探讨妊娠晚期凝血功能指标及血小板参数的变化。方法对70例妊娠晚期和80例健康体检非妊娠妇女分别进行凝血功能四项指标、D-二聚体及血小板检测,比较两组检测结果。结果观察组患者血清平均PT、APTT、TT显著缩短,血小板计数显著下降,FIB、D-二聚体含量和血小板体积分布宽度显著升高(P<0.05);两组血小板平均体积、血小板压积比较差异均无显著性(P>0.05)。结论晚期妊娠各项凝血指标和血小板参数的监测,对预防产后异常出血、DIC和血栓栓塞具有重要的临床意义。

Objective To explore the change and clinical significance of coagulation indicators and platelet param- eters in late pregnant women. Methods The four coagulation indicators, D-dimer and platelet in 80 cases late pregnant women and 70 cases nomal women were detected, compare detection consequence of two groups. Results Compared with the control group, PT, APTT and TT in observation group was significant shorter, the count of PLT was decreased, FIB, DD and PDW was significantly higher（P 〈 0.05）, but MPV and PCT were not statisticaUy significant. Conclusion Monitor of coagulation indicators and platelet parameters for late pregnant women, is important to prevent the occurrence of abnormal bleeding, DIC and thromboembolism.