恶性肿瘤患者糖代谢异常的研究进展

The research advance in malignant tumor patients with glycometabolism disorder

肿瘤细胞的糖代谢异常普遍地存在于多数肿瘤疾病中,糖酵解途径增强是肿瘤细胞物质代谢中最主要的特点,但随着分子生物学的发展及基因转染技术的兴起,这一理论出现了一些新观点和进展。本文着重就肿瘤细胞糖代谢的特点、机制、糖代谢异常与肿瘤的发生及其他营养物质代谢混乱关系的最新研究成果做一综述,并总结近年来肿瘤代谢的治疗情况。

The glycometabolism disorder is commonly seen in many types of tumor cells. Increasing glycolytic pathmay is the major characteristic in substance metabolism of tumor cells. However, with development of molecular biology and rise of gene transfection technology,new ideas and progress appeared.Our study focused on reviewing the recent development of characteristic and mechanisms in tumor cell glycometabolism. And it also paid attention to the recent studies on the relationship between glycometabolism and other nutrition metabolism disorder. Finally,the related works on therapy were summarized according to the recent research for tumor metabolism.