摘要
目的：采用Meta分析方法研究高温茶水对人群食管癌患病风险的影响。方法：以茶、温度和食管癌为主题词及关键词,联合检索1966-2014年4月Medline、Pubmed、Embase、Cochrane数据库发表的相关文献。使用STATA 12.0软件进行效应值的合并和异质性检验,通过漏斗图、Begg和Egger回归计算发表偏倚。结果：本次研究共纳入9篇文献,包括3261名食管癌病例。通过比较饮用高温茶水组和饮用非高温茶水组食管癌的患病风险,高温茶水能够使食管癌患病风险增高（合并OR=2.21,95%CI 1.95-2.51,Z=12.50,P〈0.000 01）,通过Begg’s轶相关检验法得出Pr〉｜Z｜=0.858〉0.05;Egger’s回归法得出P=0.74〉0.05,说明纳入文献发表偏倚较小。结论：高温茶水可能会增加人群食管癌的患病风险,但目前研究证据还比较有限。
Objective：To explore the correlation between hot tea drinking and risk of Esophageal cancer through Meta-analysis.Method：Relative studies published between 1966 to April 2014 about tea and risk of esophageal cancer were searched in Pubmed,Embase,Cochrane Data.The merging effect value and homogeneity were analyzed by using STATA 12.0 software,and the funnel plot,Begg＇s and Egger＇s test were adopted to examine the potential publication bias.Result：A total of 9 publications with 3261 esophageal cancer cases were included.Based on the comparison between the hot tea drinking group and not-hot tea drinking group,hot tea drinking was significantly increased the esophageal cancer risk（OR=2.21,95%CI 1.95-2.51,Z=12.50,P〈0.000 01）.There was no publication bias in these literatures by Begg＇s test（Pr｜Z｜=0.858〉0.05） and Egger＇s test（P=0.74〉0.05）.Conclusion：Hot tea drinking may increase the risk of esophageal cancer.
出处
《中外医学研究》
2014年第36期11-14,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
茶水
高温
食管癌
META分析
Tea
High temperature
Esophageal cancer
Meta-analysis
