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胰高血糖素样肽-1与2型糖尿病骨质疏松 被引量:1

Glucagon like peptide-1 and osteoporosis in patients with type 2 diabetes mellitus
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摘要 新近研究发现胰高血糖素样肽-1(GLP-1)不仅能促进胰岛素释放、调节血糖动态平衡,还具有抑制骨吸收、增加骨形成的作用。本文就GLP-1对2型糖尿病骨质疏松的作用机制作一综述。 Recent studies show that glucagon like peptide-1 (GLP-1) can not only promote releasing insulin, regulate glucose dynamic balance, but also inhibit bone absorption and stimulate bone formation. This paper reviewed the mechanism of GLP-1 on osteoporosis in patients with type 2 diabetes meUitus.
作者 张燕 杨秋萍
出处 《中华临床医师杂志(电子版)》 CAS 2014年第21期113-116,共4页 Chinese Journal of Clinicians(Electronic Edition)
关键词 糖尿病 骨质疏松 胰高血糖素样肽1 Diabetes mcllitus Osteoporosis Glucagon-like peptide 1
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  • 1Poole KE, van Bezooijen RL, Loveridge N, et al. Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation. FASEB J 2005; 19: 1842-4.
  • 2Moester MJ, Papapoulos SE, t.owlk CW, et al. Sclerostin: Current knowledge and future perspectives. Calcif Tissue Int 2010; 87: 99-107.
  • 3Terpos E, Fragiadaki K, Konsta M, et al. Early effects of IL-6 receptor inhibition on bone homeostasis: A pilot study in women with rheumatoid arthritis. Clin Exp Rheumatol 2011; 29: 921-5.
  • 4Cejka D, Herberth J, Branscum AJ, et al. Sclerostin and Dickkopf-l in renal osteodystrophy. Clin J Am Soc Nephrol 2011; 6: 877-82.
  • 5Cejka D, Jager-Lansky A, Kieweg H, et al. Sclerostin serum levels correlate positively with bone mineral density and microarchitecture in haemodialysis patients. Nephrol Dial Transplant 2012; 27: 226-30.
  • 6Madder UI, Hoey KA, Amin S, et al. Relation of age, gender, and bone mass to circulating sclerostin levels in women and men. J Bone Miner Res 2011; 26: 373-9.
  • 7Mirza FS, Padhi ID, Raisz LG, et al. Serum sclerostin levels negatively correlate with parathyroid hormone levels and free estrogen index in postmenopausal women. J Clin Endocrinol Metab 2010; 95: 1991-7.
  • 8Garda-Martin A, Rozas-Moreno P, Reyes-Garda R, et al. Circulating levels of sclerostin are increased in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 2012; 97: 234-41.
  • 9Gennari L, Merlotti D, Valenti R, et al. Circulating sclerostin levels and bone turnover in type 1 and type 2 diabetes. J Clin Endocrinol Metab 2012; 97: 1737-44.
  • 10McNulty M, Singh RJ, Li X, et al. Determination of serum and plasma sclerostin concentrations by enzymelinked immunoassays. J Clin Endocrinol Metab 2011; 96: E1159-62.

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