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三阴性乳腺癌术后辅助TEC方案化疗的疗效及预后 被引量:1

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摘要 目的:探讨TEC化疗方案治疗术后三阴性乳腺癌的临床疗效。方法:对接受6个周期TEC化疗方案治疗的36例三阴性乳腺癌进行回顾性研究,分析近远期化疗疗效。结果:化疗后随访18-24个月,中位22.8个月;36例患者中30例未出现局部复发和远处转移,总有效率为83.33%。主要不良反应包括中性粒细胞减少31例(86.11%),中性粒细胞减少性发热3例(8.33%),恶心、呕吐30例(83.33%),腹泻8例(22.22%),口腔黏膜炎5例(13.89%),乏力虚弱22例(61.11%),术后死亡1例,局部复发3例,远处转移2例,2年生存率为97.22%。结论:对三阴性乳腺癌(TNBC)在早期给予正确有效的治疗可显著提高患者的生存率,而目前蒽环联合紫杉醇的TEC辅助化疗有利于提高TNBC术后治疗效果,在改善患者的生活质量、提高患者生存率等方面也发挥着不可低估的作用和意义。
出处 《吉林医学》 CAS 2014年第36期8086-8087,共2页 Jilin Medical Journal
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